Publications

Filter by type:

Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo (2017)

Details Get it

Dissecting the molecular assembly of the Toxoplasma gondii MyoA motility complex (2017)

Details Get it

Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion (2017)

Details Get it

Not a simple tether: Binding of Toxoplasma gondii AMA1 to RON2 during invasion protects AMA1 from rhomboid-mediated cleavage and leads to dephosphorylation of its cytosolic tail (2016)

Details Get it

Global Analysis of Palmitoylated Proteins in Toxoplasma gondii (2015)

Details Get it

Yeast three-hybrid screen identifies TgBRADIN as a novel negative regulator of Toxoplasma gondii bradyzoite differentiation (2015)

Details Get it

A Toxoplasma gondii class XIV myosin, expressed in Sf9 cells with a parasite co-chaperone, requires two light chains for fast motility (2014)

Details Get it

Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii (2014)

Details Get it

Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle (2014)

Details Get it

Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay (2014)

Details Get it

Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion (2014)

Details Get it

Identification of Cryptosporidium parvum active chemical series by repurposing the open access malaria box (2014)

Details Get it

A modular approach to triazole-containing chemical inducers of dimerisation for yeast three-hybrid screening (2013)

Details Get it

Toxoplasma gondii Chemical Biology (2013)

Details Get it

Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication (2012)

Details Get it

Targeted disruption of TgPhIL1 in Toxoplasma gondii results in altered parasite morphology and fitness (2011)

Details Get it

Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion (2011)

Details Get it

Toxoplasma gondii transmembrane microneme proteins and their modular design (2010)

Details Get it

A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity (2010)

Details Get it

GAP45 phosphorylation controls assembly of the Toxoplasma myosin XIV complex (2009)

Details Get it

Synthesis and Biological Evaluation of Functionalised Tetrahydro-B-carboline Analogues as Inhibitors of Toxoplasma gondii Invasion (2009)

Details Get it

Identification of conoidin A as a covalent inhibitor of peroxiredoxin II (2009)

Details Get it

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility (2008)

Details Get it

Current and emerging approaches to studying invasion in apicomplexan parasites (2008)

Details Get it

Targeting invasion and egress: from tools to drugs? (2007)

Details Get it

Synthesis and chemical characterisation of target identification reagents based on an inhibitor of human cell invasion by the parasite Toxoplasma gondii (2007)

Details Get it

Identification of PhIL1, a novel cytoskeletal protein of the Toxoplasma gondii pellicle, through photosensitized labeling with 5-[125I]iodonaphthalene-1-azide (2006)

Details Get it

Targeted deletion of MIC5 enhances trimming proteolysis of Toxoplasma invasion proteins (2006)

Details Get it

Laser scanning cytometer-based assays for measuring host cell attachment and invasion by the human pathogen Toxoplasma gondii (2006)

Details Get it

Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles (2005)

Details Get it

Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion (2005)

Details Get it

A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii (2004)

Details Get it

Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii (2004)

Details Get it

The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells (2004)

Details Get it

Biosynthesis of glycosylphosphatidylinositol is essential to the survival of the protozoan parasite Toxoplasma gondii (2003)

Details Get it

Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins (2002)

Details Get it

Using small molecules to study big questions in cellular microbiology (2002)

Details Get it

Identification and molecular characterization of GRA8, a novel, proline-rich, dense granule protein of Toxoplasma gondii (2000)

Details Get it

The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels (2000)

Details Get it

Distamycin A selectively inhibits Acanthamoeba RNA synthesis and differentiation (1999)

Details Get it

Novel secretory pathways in Plasmodium? (1999)

Details Get it

96-Well plates providing high optical resolution for high-throughput, immunofluorescence-based screening of monoclonal antibodies against Toxoplasma gondii (1999)

Details Get it

Actin-binding proteins of invasive malaria parasites and the regulation of actin polymerization by a complex of 32/34-kDa proteins associated with heat shock protein 70kDa (1998)

Details Get it

Rab GTPases and the unusual secretory pathway of plasmodium (1997)

Details Get it

Identification of a family of Rab G-proteins in Plasmodium falciparum and a detailed characterisation of pfrab6 (1996)

Details Get it

Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore (1996)

Details Get it

Invasion of Erythrocytes by Malarial Merozoites (1994)

Details Get it

Staurosporine inhibits invasion of erythrocytes by malarial merozoites (1994)

Details Get it

The origin of parasitophorous vacuole membrane lipids in malaria-infected erythrocytes (1993)

Details Get it

The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites (1990)

Details Get it

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C (1990)

Details Get it

Dephosphorylation of sea urchin sperm guanylate cyclase during fertilization (1986)

Details Get it

Phosphorylation of membrane-bound guanylate cyclase of sea urchin spermatozoa (1986)

Details Get it

Effects of extracellular egg factors on sperm guanylate cyclase (1985)

Details Get it

Chemotaxis of Arbacia punctulata spermatozoa to resact, a peptide from the egg jelly layer (1985)

Details Get it

A peptide associated with eggs causes a mobility shift in a major plasma membrane protein of spermatozoa (1984)

Details Get it

The increased phosphorylation of ribosomal protein S6 in Arbacia punctulata is not a universal event in the activation of sea urchin eggs (1983)

Details Get it

Dephosphorylation of a major sperm membrane protein is induced by egg jelly during sea urchin fertilization (1983)

Details Get it