Toxoplasma Invasion 2

Invasion of a T. gondii tachyzoite into a human foreskin fibroblast. Note the constriction in the parasite’s plasma membrane that moves from anterior to posterior as the parasite penetrates past the host plasma membrane and into the developing parasitophorous vacuole. Real time; filmed at 35oC using a Dage VE1000SIT camera mounted on a Nikon Eclipse E400 microscope (Nomarski optics). The parasite is ~7um long.