CDPK2A and CDPK1 form a signaling module upstream of Toxoplasma motility (2023)
Shortt, E., Hackett, C.G., Stadler, R.V., Kent, R.S., Herneisen, A.L., Ward, G.E., Lourido, S.
The class XIV myosin of Toxoplasma gondii, TgMyoA, is druggable in an animal model of infection (2023)
Kelsen, A., Kent, R.S., Snyder, A.K., Wehri, E., Bishop, S.J., Stadler, R.V., Powell, C., Martorelli di Genova, B., Rompikuntal, P.K., Boulanger, M.J., Warshaw, D.M., Westwood, N.J., Schaletzky, J., Ward, G.E.
A circular zone of attachment to the extracellular matrix provides directionality to the motility of Toxoplasma gondii in 3D (2022)
Stadler, R.V., Nelson, S.R., Warshaw, D.M., Ward, G.E.
The potent Toxoplasma gondii growth inhibitor QQ-437 does not bind to its predicted target, parasite adaptin3𝛽, in yeast three-hybrid assays (2022)
Tran, F., Foderaro, J, Westwood, N.J.*, Ward, G.E.
Blocking palmitoylation of Toxoplasma gondii myosin light chain 1 disrupts glideosome composition but has little impact on parasite motility (2021)
Rompikuntal P, Foe IT, Deng B, Bogyo M, Ward GE.
Differential requirements of cyclase associated protein (CAP) for actin turnover during the lytic cycle of Toxoplasma gondii (2019)
Hunt, A., Wagener, J., Kent, R., Carmeille, R., Russell, M., Peddie, C., Collinson, L., Heaslip, A., Ward, G.E., Treeck, M.
Lightweight and Scalable Particle Tracking and Motion Clustering of 3D Cell Trajectories (2019)
Fazli, M.S., Stadler, R.V., Alaila, B.E., Vella, S.A., Moreno, S.N.J., Ward, G.E. and Quinn, S.
Structural and mechanistic insights into the function of the unconventional class-XIV myosin, MyoA, from Toxoplasma gondii (2018)
Powell, C.J., Ramaswamy, R., Kelsen, A., Hamelin, D.J., Warshaw, D.M., Bosch, J., Burke, J.E., Ward, G.E., and Boulanger, M.J.
Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion (2017)
Whitelaw, J.A., Latorre-Barragan, F., Gras, S., Pall, G.S., Leung, J.M., Heaslip., A., Egarter, S., Andenmatten, N., Nelson, S.R., Warshaw, D.M, Ward, G.E., Meissner, M.
Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo (2017)
Gras, S., Jackson, A., Woods, S., Pall, G., Whitelaw, J., Leung, J.M., Ward, G.E., Roberts, C.W., Meissner, M.
Not a simple tether: Binding of Toxoplasma gondii AMA1 to RON2 during invasion protects AMA1 from rhomboid-mediated cleavage and leads to dephosphorylation of its cytosolic tail (2016)
Krishnamurthy, S.K., Deng, B., del Rio, R., Buchholz, K.R., Treck, M., Urban, S., Boothroyd, J., Lam, Y.-W., Ward., G.E.
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii (2015)
Foe, I.T., Child, M.A, Majmudar, J.D., Krishnamurthy, S. van der Linden, W.A, Ward, G.E., Martin, B. R and Bogyo, M.
Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion (2014)
Leung, J.M., Tran, F., Pathak, R.B., Poupart, S., Heaslip, A.T., Ballif, B.A., Westwood, N.J.* and Ward, G.E.*
Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle (2014)
Tilley, L.D., Krishnamurthy, S., Westwood, N.J. and Ward, G.E.
A Toxoplasma gondii class XIV myosin, expressed in Sf9 cells with a parasite co-chaperone, requires two light chains for fast motility (2014)
Bookwalter, C.S., Kelsen, A., Leung, J.M., Ward, G.E.* and Trybus, K.M.*
Identification of Cryptosporidium parvum active chemical series by repurposing the open access malaria box (2014)
Bessoff, K., Spangenberg, T., Foderaro, J.E., Jumani, R.S., Ward, G.E., Huston, C.D.
Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay (2014)
Leung, J.M., Rould, M.A., Konradt, C., Hunter, C.A., Ward, G.E.
A modular approach to triazole-containing chemical inducers of dimerisation for yeast three-hybrid screening (2013)
Tran, F., Odell, A.V., Ward, G.E., Westwood, N.J.
A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity (2010)
Heaslip, A.T., Carey, K.L., Catti, F., Warshaw, D.M., Westwood, N.J., Ballif, B.A., Ward G.E.
Identification of conoidin A as a covalent inhibitor of peroxiredoxin II (2009)
Haraldsen, J.D., Liu, G., Botting, C.H., Walton, J.G.A., Storm, J., Phalen, T.J., Kwok, L.Y., Soldati-Favre, D., Heintz, N.H., Muller, S., Westwood, N.J., Ward, G. E.
Synthesis and chemical characterisation of target identification reagents based on an inhibitor of human cell invasion by the parasite Toxoplasma gondii (2007)
Evans, K.M., Haraldsen, J.D., Pearson, R.J., Slawin, A.M.Z, Ward, G.E., Westwood, N.J.
Laser scanning cytometer-based assays for measuring host cell attachment and invasion by the human pathogen Toxoplasma gondii (2006)
Mital, J., Schwarz, J. Taatjes, D.J., Ward, G.E.
Identification of PhIL1, a novel cytoskeletal protein of the Toxoplasma gondii pellicle, through photosensitized labeling with 5-[125I]iodonaphthalene-1-azide (2006)
Gilk, S.D., Raviv, Y., Hu, K., Murray, J.M., Beckers, C.J.M., Ward, G.E.
Targeted deletion of MIC5 enhances trimming proteolysis of Toxoplasma invasion proteins (2006)
Brydges, S.D., Zhou, X.W., Hunyh, M., Harper, J.M., Mital, J., Ajoble, D., Daubener, W., Ward, G.E., Carruthers, V.B.
Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion (2005)
Mital, J., Meissner, M., Soldati, D., Ward, G.E.
Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles (2005)
Alexander, D.L., Mital, J., Ward, G.E., Bradley, P., Boothroyd, J.
The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells (2004)
Carey, K.L., Jongco, A., Kim, K., Ward, G.E.
Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii (2004)
Gaskins, E., Gilk, S., DeVore, N. Mann, T., Ward, G., Beckers, C.J.
Biosynthesis of glycosylphosphatidylinositol is essential to the survival of the protozoan parasite Toxoplasma gondii (2003)
Wichroski, M.J., Ward, G.E.
Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins (2002)
Wichroski, M.J., Melton, J., Donahue, C.G., Tweten, R.K., Ward, G.E.
Identification and molecular characterization of GRA8, a novel, proline-rich, dense granule protein of Toxoplasma gondii (2000)
Carey, K.L., Donahue, C.G., Ward, G.E.
The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels (2000)
Donahue, C.G., Carruthers, V., Gilk, S.D., Ward, G.E.
Actin-binding proteins of invasive malaria parasites and the regulation of actin polymerization by a complex of 32/34-kDa proteins associated with heat shock protein 70kDa (1998)
Tardieux, I., Baines, I., Mossakowska, M., Ward, G.E.
Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore (1996)
Suss-Toby, E., Zimmerberg, J., Ward, G.E.
Identification of a family of Rab G-proteins in Plasmodium falciparum and a detailed characterisation of pfrab6 (1996)
de Castro, F.A., Ward, G.E., Jambou, R., Attal, G., Jaureguiberry, G., Braun-Breton, C., Chakarabarti, D., Langsley, G.
The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites (1990)
Adams, J.H., Hudson, D.E., Torii, M., Ward, G.E., Wellems, T.E., Aikawa, M., Miller, L.H.
Chemotaxis of Arbacia punctulata spermatozoa to resact, a peptide from the egg jelly layer (1985)
Ward, G.E., Brokaw, C.B., Garbers, D.L., Vacquier, V.D.
A peptide associated with eggs causes a mobility shift in a major plasma membrane protein of spermatozoa (1984)
Suzuki, N., Shimomura, H., Radany, E.W., Ramarao, C.S., Ward, G.E., Bentley, J.K., Garbers, D.L.
The increased phosphorylation of ribosomal protein S6 in Arbacia punctulata is not a universal event in the activation of sea urchin eggs (1983)
Ward, G.E., Vacquier, V.D., Michel, S.